Cart
sales@molnova.com
Home - Products - Microbiology/Virology - Fungal - Quilseconazole

Quilseconazole

CAS No. 1340593-70-5

Quilseconazole( VT-1129 | VT1129 )

Catalog No. M11366 CAS No. 1340593-70-5

A novel selective, orally available fungal CYP51 (lanosterol 14-α-demethylase) inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 262 Get Quote
50MG 1341 Get Quote
100MG 2124 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Quilseconazole
  • Note
    Research use only, not for human use.
  • Brief Description
    A novel selective, orally available fungal CYP51 (lanosterol 14-α-demethylase) inhibitor.
  • Description
    A novel selective, orally available fungal CYP51 (lanosterol 14-α-demethylase) inhibitor; displays greater selectivity for fungal enzyme than for mammalian CYP450 compared to the approved azole class of antifungal drugs; inhibits C. albicans and T. rubrum with MIC of <0.001 ug/mL, also demonstrated potent activities against Cryptococcusspecies as demonstrated by low MIC50 and MIC90 values.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    VT-1129 | VT1129
  • Pathway
    Microbiology/Virology
  • Target
    Fungal
  • Recptor
    Fungal
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1340593-70-5
  • Formula Weight
    513.376
  • Molecular Formula
    C22H14F7N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O[C@@](CN1N=NN=C1)(C2=CC=C(F)C=C2F)C(F)(F)C3=NC=C(C4=CC=C(OC(F)(F)F)C=C4)C=C3
  • Chemical Name
    (2R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-{5-[4-(trifluoromethoxy)phenyl]pyridin-2-yl}propan-2-ol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hoekstra WJ, et al. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3455-8. 2. Lockhart SR, et al. Antimicrob Agents Chemother. 2016 Mar 25;60(4):2528-31. 3. Warrilow AG, et al. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4530-8. 4. Nielsen K, et al. Med Mycol. 2017 Jun 1;55(4):453-456.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • ML316

    ML316 is a specific antifungal agent that fungal-selectively inhibits the mitochondrial phosphate carrier Mir1.

  • Flumorph

    A carboxylic acid amide (CAA) fungicide.

  • Clotrimazole

    An antifungal agent that works by altering the permeability of the fungal cell wall.

Sign In Join Free