Pyributicarb
CAS No. 88678-67-5
Pyributicarb ( TSH-888 )
Catalog No. M20997 CAS No. 88678-67-5
Pyributicarb is a potent activator of both CYP3A4 gene and human pregnane X receptor (hPXR).?
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
25MG | 43 | Get Quote |
|
50MG | 65 | Get Quote |
|
100MG | 95 | Get Quote |
|
200MG | 140 | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NamePyributicarb
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NoteResearch use only not for human use.
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Brief DescriptionPyributicarb is a potent activator of both CYP3A4 gene and human pregnane X receptor (hPXR).?
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DescriptionPyributicarb is a potent activator of both CYP3A4 gene and human pregnane X receptor (hPXR).?
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SynonymsTSH-888
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PathwayMetabolic Enzyme/Protease
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TargetP450
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RecptorCYP3A4
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Research Area——
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Indication——
Chemical Information
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CAS Number88678-67-5
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Formula Weight330.44
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Molecular FormulaC18H22N2O2S
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL (302.63 mM)
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SMILESCOc1cccc(N(C)C(=S)Oc2cccc(C(C)(C)C)c2)n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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PIK75
PIK-75 Hydrochloride is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.
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Furafylline
Furafylline is a selective inhibitor of human cytochrome P450 (CYP)1A2 (IC50 : 0.07 μM)
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Rhodionin
Rhodionin and rhodionin can inhibit cytochrome P450 2D6 non-competitively with high specificity which could have implications for interactions with co-administered drugs; they can significantly suppress the elevation of the postprandial blood triglyceride level suggests that they may be to the treatment of lifestyle-related diseases such as hyperlipidemia and exogeneous obesity and to health foods.