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PIK75
CAS No. 372196-67-3
PIK75 ( —— )
Catalog No. M18485 CAS No. 372196-67-3
PIK-75 Hydrochloride is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 36 | In Stock |
|
| 10MG | 47 | In Stock |
|
| 25MG | 102 | In Stock |
|
| 50MG | 180 | In Stock |
|
| 100MG | 324 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePIK75
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NoteResearch use only, not for human use.
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Brief DescriptionPIK-75 Hydrochloride is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.
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DescriptionPIK-75 Hydrochloride is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetP450
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RecptorDNA-PK; p110α; p110β; p110γ; p110δ
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Research Area——
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Indication——
Chemical Information
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CAS Number372196-67-3
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Formula Weight452.28
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Molecular FormulaC16H14BrN5O4S
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Purity98%
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Solubility——
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SMILESCC1=C(C=C(C=C1)[N+](=O)[O-])S(=O)(=O)N(C)/N=C/C2=CN=C3N2C=C(C=C3)Br
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zheng Z, et al. Mol Pharmacol. 2011, 80(4), 657-664.
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