Psychosine( —— )

Catalog No. M33713 CAS No. 2238-90-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

Psychosine
Note

Research use only, not for human use.
Brief Description

Psychosine (Galactosylsphingosine) is a PKC inhibitor, a substrate for the enzyme galactosylceramide cerebrosidase (GALC), and a potential biomarker of Krabbe's disease.
Description

Psychosine (Galactosylsphingosine), a substrate of the galactocerebrosidase (GALC) enzyme, is a potential biomarker for Krabbe disease. Psychosine is a highly cytotoxic lipid, capable of inducing cell death in a wide variety of cell types including, most relevantly to globoid cell leukodystrophy (GLD), oligodendrocytes. Psychosine causes cell death at least in part via apoptosis.Psychosine also is an inhibitor of PKC.
In Vitro

Cell Viability Assay Cell Line:Oligodendrocyte cells, M03.13 Concentration:10, 20, and 40 μM Incubation Time:24 hours Result:Caused cell death at least in part via apoptosis.
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

PKC
Recptor

PKC
Research Area

——
Indication

——

CAS Number

2238-90-6
Formula Weight

461.63
Molecular Formula

C24H47NO7
Purity

>98% (HPLC)
Solubility

——
SMILES

CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)CO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O
Chemical Name

——

1. M L Escolar, et al. Psychosine, a marker of Krabbe phenotype and treatment effect. Mol Genet Metab. 2017 Jul;121(3):271-278.?

Calculator

molnova catalog