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Praliciguat

CAS No. 1628730-49-3

Praliciguat( IW-1973 )

Catalog No. M26793 CAS No. 1628730-49-3

Praliciguat stimulates sGC in HEK-293 cells (EC50: 197 nM). Praliciguat is an effective and orally active soluble guanylate cyclase stimulator.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Praliciguat
  • Note
    Research use only, not for human use.
  • Brief Description
    Praliciguat stimulates sGC in HEK-293 cells (EC50: 197 nM). Praliciguat is an effective and orally active soluble guanylate cyclase stimulator.
  • Description
    Praliciguat stimulates sGC in HEK-293 cells (EC50: 197 nM). Praliciguat is an effective and orally active soluble guanylate cyclase stimulator. It also enhances NO signaling and acts as a vasodilator.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    IW-1973
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Alkyl/ether| Cleavable| PEGs
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1628730-49-3
  • Formula Weight
    534.37
  • Molecular Formula
    C21H14F8N6O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (467.85 mM)
  • SMILES
    OC(CNc1nc(ncc1F)-c1cc(-c2ccon2)n(Cc2ccccc2F)n1)(C(F)(F)F)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Carston R. Wagner, et al. Protein nanorings. US8236925B1.
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