Posaconazole ( SCH-56592 )

Catalog No. M12610 CAS No. 171228-49-2

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Posaconazole
Note

Research use only, not for human use.
Brief Description

A triazole antifungal agent that blocks the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase and accumulation of methylated sterol precursors.
Description

A triazole antifungal agent that blocks the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase and accumulation of methylated sterol precursors, more potent at inhibiting 14α-demethylase than itraconazole.Fungal Infection Approved
Synonyms

SCH-56592
Pathway

Microbiology/Virology
Target

Fungal
Recptor

Others
Research Area

Infection
Indication

Fungal Infection

CAS Number

171228-49-2
Formula Weight

700.78
Molecular Formula

C37H42F2N8O4
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

O=C1N([C@@H](CC)[C@@H](O)C)N=CN1C2=CC=C(N3CCN(C4=CC=C(OC[C@@H]5CO[C@@](CN6N=CN=C6)(C7=CC=C(F)C=C7F)C5)C=C4)CC3)C=C2
Chemical Name

D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-