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Pomalidomide-PEG4-C-COOH

CAS No. 2097938-44-6

Pomalidomide-PEG4-C-COOH( Cereblon Ligand -Linker Conjugates 1 | E3 Ligase Ligand-Linker Conjugates 1 )

Catalog No. M26874 CAS No. 2097938-44-6

Pomalidomide-PEG4-C-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Pomalidomide-PEG4-C-COOH
  • Note
    Research use only, not for human use.
  • Brief Description
    Pomalidomide-PEG4-C-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
  • Description
    Pomalidomide-PEG4-C-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Cereblon Ligand -Linker Conjugates 1 | E3 Ligase Ligand-Linker Conjugates 1
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    V-domain Ig suppressor of T-cell activation (VISTA)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2097938-44-6
  • Formula Weight
    507.496
  • Molecular Formula
    C23H29N3O10
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (98.52 mM)
  • SMILES
    OC(=O)COCCOCCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gabr MT, Gambhir SS. Discovery and Optimization of Small-Molecule Ligands for V-Domain Ig Suppressor of T-Cell Activation (VISTA). J Am Chem Soc. 2020 Sep 23;142(38):16194-16198.
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