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Pomalidomide-PEG1-CO2H

CAS No. 2139348-60-8

Pomalidomide-PEG1-CO2H( Pomalidomide-PEG1-C2-COOH )

Catalog No. M28266 CAS No. 2139348-60-8

Pomalidomide-PEG1-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Pomalidomide-PEG1-CO2H
  • Note
    Research use only, not for human use.
  • Brief Description
    Pomalidomide-PEG1-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.
  • Description
    Pomalidomide-PEG1-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.(In Vitro):PROTACs contain two distinct ligands, one for the E3 ubiquitin ligase and the other for the target protein, linked by a linker.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Pomalidomide-PEG1-C2-COOH
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    HBV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2139348-60-8
  • Formula Weight
    389.36
  • Molecular Formula
    C18H19N3O7
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (321.04 mM)
  • SMILES
    O=C(O)CCOCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Campagna MR, et al. Sulfamoylbenzamide derivatives inhibit the assembly of hepatitis B virus nucleocapsids. J Virol. 2013 Jun;87(12):6931-42.
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