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NLRP3/AIM2-IN-2
CAS No. 791840-86-3
NLRP3/AIM2-IN-2( —— )
Catalog No. M35414 CAS No. 791840-86-3
NLRP3/AIM2-IN-2 is a novel potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome dependent pyroptosis with IC50 of 0.2392 ± 0.0233 μ M.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 49 | In Stock |
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| 5MG | 45 | In Stock |
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| 10MG | 76 | In Stock |
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| 25MG | 155 | In Stock |
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| 50MG | 230 | In Stock |
|
| 100MG | 346 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 808 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNLRP3/AIM2-IN-2
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NoteResearch use only, not for human use.
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Brief DescriptionNLRP3/AIM2-IN-2 is a novel potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome dependent pyroptosis with IC50 of 0.2392 ± 0.0233 μ M.
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DescriptionNLRP3/aim2-in-2 (compound 8) is a new potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome dependent cell death. Its < b > IC < sub > 50 < / sub > < / b > value is 0.2392 ± 0.0233 μ M。
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorAIM2
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Research Area——
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Indication——
Chemical Information
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CAS Number791840-86-3
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Formula Weight257.28
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Molecular FormulaC15H15NO3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (485.85 mM; Ultrasonic )
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SMILESCOc1ccc(CC(=O)Nc2cccc(O)c2)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194.?
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