NLRP3/AIM2-IN-2( —— )

Catalog No. M35414 CAS No. 791840-86-3

NLRP3/AIM2-IN-2 is a novel potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome dependent pyroptosis with IC50 of 0.2392 ± 0.0233 μ M.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	49	In Stock
5MG	45	In Stock
10MG	76	In Stock
25MG	155	In Stock
50MG	230	In Stock
100MG	346	In Stock
200MG	Get Quote	In Stock
500MG	808	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

NLRP3/AIM2-IN-2
Note

Research use only, not for human use.
Brief Description

NLRP3/AIM2-IN-2 is a novel potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome dependent pyroptosis with IC50 of 0.2392 ± 0.0233 μ M.
Description

NLRP3/aim2-in-2 (compound 8) is a new potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome dependent cell death. Its < b > IC < sub > 50 < / sub > < / b > value is 0.2392 ± 0.0233 μ M。
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

AIM2
Research Area

——
Indication

——

Chemical Information

CAS Number

791840-86-3
Formula Weight

257.28
Molecular Formula

C15H15NO3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (485.85 mM; Ultrasonic )
SMILES

COc1ccc(CC(=O)Nc2cccc(O)c2)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194.?

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