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Poloxin
CAS No. 321688-88-4
Poloxin ( —— )
Catalog No. M24255 CAS No. 321688-88-4
Poloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 43 | In Stock |
|
| 25MG | 104 | In Stock |
|
| 50MG | 185 | In Stock |
|
| 100MG | 275 | In Stock |
|
| 200MG | 410 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePoloxin
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NoteResearch use only, not for human use.
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Brief DescriptionPoloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).
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DescriptionPoloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetPLK
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RecptorPLK1;PLK2;PLK3
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Research Area——
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Indication——
Chemical Information
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CAS Number321688-88-4
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Formula Weight297.4
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Molecular FormulaC18H19NO3
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Purity>98% (HPLC)
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SolubilityDMSO:14 mg/mL (43.72 mM; Need ultrasonic)
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SMILESCC(C)C(C(C=C1C)=O)=C/C1=N/OC(c1c(C)cccc1)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Yuan J, et al. Polo-box domain inhibitor poloxin activates the spindle assembly checkpoint and inhibits tumor growth in vivo. Am J Pathol. 2011 Oct;179(4):2091-9.
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