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3MB-PP1
CAS No. 956025-83-5
3MB-PP1( —— )
Catalog No. M27450 CAS No. 956025-83-5
3MB-PP1 is an inhibitor of Polo-like kinase 1 (PLK1) and inhibits Leu93 Mutant Zipper-interacting protein kinase (Leu93-ZIPK) with an IC50 of 2 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 50 | In Stock |
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| 5MG | 46 | In Stock |
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| 10MG | 84 | In Stock |
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| 25MG | 169 | In Stock |
|
| 50MG | 263 | In Stock |
|
| 100MG | 386 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name3MB-PP1
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NoteResearch use only, not for human use.
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Brief Description3MB-PP1 is an inhibitor of Polo-like kinase 1 (PLK1) and inhibits Leu93 Mutant Zipper-interacting protein kinase (Leu93-ZIPK) with an IC50 of 2 μM.
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Description3MB-PP1 is an inhibitor of Polo-like kinase 1 (PLK1) and inhibits Leu93 Mutant Zipper-interacting protein kinase (Leu93-ZIPK) with an IC50 of 2 μM. 3MB-PP1 can be used in studies about cell division and hypha formation of Candida albicans.(In Vitro):In a strain bearing analog-sensitive alleles of SSN3(Cdk8), 3MB-PP1 (5 μM) stimulates hyphal growth.
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In Vitro3MB-PP1 (5 μM; 3 hours) stimulates hyphal growth in a strain bearing analog-sensitive alleles of SSN3.
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetPLK
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RecptorBTK
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Research Area——
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Indication——
Chemical Information
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CAS Number956025-83-5
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Formula Weight295.38
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Molecular FormulaC17H21N5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (338.55 mM)
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SMILESN=1C=NC2=C(C1N)C(=NN2C(C)(C)C)CC=3C=CC=C(C3)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Somana Siva Prasad, et al. A QUALITY BY DESIGN APPROACH FOR DEVELOPMENT OF SIMPLE AND ROBUST REVERSED PHASE STABILITY INDICATING HPLC METHOD FOR ESTIMATION OF IBRUTINIB AND ITS IMPURITIES.
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