
Piroxicam
CAS No. 36322-90-4
Piroxicam( Feldene | Larapam | NSC 666076 )
Catalog No. M14246 CAS No. 36322-90-4
Piroxicam is a non-selective COX inhibitor.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
500MG | 41 | In Stock |
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1G | 48 | In Stock |
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Biological Information
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Product NamePiroxicam
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NoteResearch use only, not for human use.
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Brief DescriptionPiroxicam is a non-selective COX inhibitor.
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DescriptionPiroxicam is a non-selective COX inhibitor.(In Vitro):Piroxicam (CP-16171) is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC50s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively. Piroxicam (CP-16171) (167, 333, 500 μM) decreases cell population of T24 and the 5637 cells. Piroxicam (CP-16171) (500 μM) also reduces the cell viability of T24 and 5637 cell, and is significantly effective when combined with 0.05 μM carboplatin. The combination also inhibits Ki-67 expression in booth cells.(In Vivo):Piroxicam (CP-16171) (0.3 mg/kg qd 24-h p.o.) reduces tumor volume in 12 of 18 dogs, and such and effect is via induction of apoptosis and reduction in urine basic fibroblast growth factor concentration.
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In VitroPiroxicam (CP-16171) is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC50s of 47, 25 μM for humanmonocyte COX-1 and COX-2, respectively. Piroxicam (CP-16171) (167, 333, 500 μM) decreases cell population of T24 and the 5637 cells. Piroxicam (CP-16171) (500 μM) also reduces the cell viability of T24 and 5637 cell, and is significantly effective when combined with 0.05 μM carboplatin. The combination also inhibits Ki-67 expression in booth cells.
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In VivoPiroxicam (CP-16171) (0.3 mg/kg qd 24-h p.o.) reduces tumor volume in 12 of 18 dogs, and such and effect is via induction of apoptosis and reduction in urine basic fibroblast growth factor concentration.
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SynonymsFeldene | Larapam | NSC 666076
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PathwayChromatin/Epigenetic
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TargetCOX
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RecptorCOX
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number36322-90-4
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Formula Weight331.35
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Molecular FormulaC15H13N3O4S
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Purity>98% (HPLC)
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SolubilityEthanol: 1 mg/mL (3.01 mM); DMSO: 66 mg/mL (199.18 mM)
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SMILESCN1C(=C(C2=CC=CC=C2S1(=O)=O)O)C(=O)NC3=CC=CC=N3
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Chemical Name4-hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Blanco FJ, et al. J Rheumatol. 1999 Jun;26(6):1366-73.
molnova catalog



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