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Piperlongumine
CAS No. 20069-09-4
Piperlongumine ( Piplartine )
Catalog No. M13131 CAS No. 20069-09-4
A naturally occurring small molecule recently identified to be toxic selectively to cancer cells in vitro and in vivo.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 27 | In Stock |
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| 25MG | 45 | In Stock |
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| 50MG | 72 | In Stock |
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| 100MG | 110 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePiperlongumine
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NoteResearch use only, not for human use.
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Brief DescriptionA naturally occurring small molecule recently identified to be toxic selectively to cancer cells in vitro and in vivo.
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DescriptionA naturally occurring small molecule recently identified to be toxic selectively to cancer cells in vitro and in vivo; elevates cellular levels of reactive oxygen species (ROS) selectively in cancer cell lines, potently inhibits the growth of spontaneously formed malignant breast tumours and their associated metastases in mice; inhibits the STAT3 signal pathway in MM cells by binding directly to the STAT3 Cys712 residue.
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SynonymsPiplartine
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PathwayJAK/STAT Signaling
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TargetSTAT
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RecptorROS
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number20069-09-4
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Formula Weight317.34
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Molecular FormulaC17H19NO5
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Purity>98% (HPLC)
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SolubilityDMSO: 31.7 mg/mL (100 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESO=C1C=CCCN1C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O
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Chemical Name5,6-dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-2(1H)-pyridinone
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Raj L, et al. Nature. 2011 Jul 13;475(7355):231-4.
2. Adams DJ, et al. Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15115-20.
3. Yao Y, et al. Oncotarget. 2016 Nov 8;7(45):73497-73508.
2. Adams DJ, et al. Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15115-20.
3. Yao Y, et al. Oncotarget. 2016 Nov 8;7(45):73497-73508.
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