Cart
sales@molnova.com
Home - Products - JAK/STAT Signaling - STAT - InS3-54

InS3-54

CAS No. 328998-92-1

InS3-54( —— )

Catalog No. M14082 CAS No. 328998-92-1

An STAT3 inhibitor that selectively targets the DNA-binding domain of STAT3.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    InS3-54
  • Note
    Research use only, not for human use.
  • Brief Description
    An STAT3 inhibitor that selectively targets the DNA-binding domain of STAT3.
  • Description
    An STAT3 inhibitor that selectively targets the DNA-binding domain of STAT3, without affecting the activation and dimerization of STAT3; preferentially suppresses proliferation of cancer over non-cancer cells and inhibits migration and invasion of malignant cells; selectively inhibits STAT3 binding to DNA without affecting the activation and dimerization of STAT3; inhibits expression of STAT3 downstream target genes and STAT3 binding to chromatin in situ.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    STAT
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    328998-92-1
  • Formula Weight
    412.401
  • Molecular Formula
    C24H16N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    (E)-4-(3-(4-nitrobenzylidene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Huang W, et al. ACS Chem Biol. 2014 May 16;9(5):1188-96. 2. Huang W, et al. Oncogene. 2016 Feb 11;35(6):783-92.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • CAY10784

    CAY10784 (STAT3-IN-17) is a STAT3 inhibitor with antiproliferative and antitumor activities. CAY10784 showed antibacterial activity against Clostridium difficile.

  • AS2863619

    AS2863619 is an orally active?inhibitor of cyclin-dependent kinase 8 (CDK8) and CDK19 (IC50s of 0.61 nM and 4.28 nM, respectively).

  • Asunaprevir

    Asunaprevir is an effective hepatitis C virus (HCV) NS3 protease inhibitor.

Sign In Join Free