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InS3-54
CAS No. 328998-92-1
InS3-54( —— )
Catalog No. M14082 CAS No. 328998-92-1
An STAT3 inhibitor that selectively targets the DNA-binding domain of STAT3.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameInS3-54
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NoteResearch use only, not for human use.
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Brief DescriptionAn STAT3 inhibitor that selectively targets the DNA-binding domain of STAT3.
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DescriptionAn STAT3 inhibitor that selectively targets the DNA-binding domain of STAT3, without affecting the activation and dimerization of STAT3; preferentially suppresses proliferation of cancer over non-cancer cells and inhibits migration and invasion of malignant cells; selectively inhibits STAT3 binding to DNA without affecting the activation and dimerization of STAT3; inhibits expression of STAT3 downstream target genes and STAT3 binding to chromatin in situ.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayJAK/STAT Signaling
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TargetSTAT
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RecptorSTAT
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Research Area——
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Indication——
Chemical Information
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CAS Number328998-92-1
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Formula Weight412.401
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Molecular FormulaC24H16N2O5
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(E)-4-(3-(4-nitrobenzylidene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Huang W, et al. ACS Chem Biol. 2014 May 16;9(5):1188-96.
2. Huang W, et al. Oncogene. 2016 Feb 11;35(6):783-92.
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