Pinoresinol

CAS No. 487-36-5

Pinoresinol ( (+)-Pinoresinol )

Catalog No. M24442 CAS No. 487-36-5

Pinoresinol has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative stress preserving pial blood flow distribution.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 160 In Stock
10MG 258 In Stock
25MG 440 In Stock
50MG 617 In Stock
100MG 872 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Pinoresinol
  • Note
    Research use only, not for human use.
  • Brief Description
    Pinoresinol has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative stress preserving pial blood flow distribution.
  • Description
    Pinoresinol has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative stress preserving pial blood flow distribution; it may exert pharmacologically interesting effects via modulation of the insulin-like signalling pathway in C.elegans. Pinoresinol causes an upregulation of the CDK inhibitor p21(WAF1/Cip1) both at mRNA and protein levels, inhibits NF-kappaB and activating protein 1 (AP-1).
  • Synonyms
    (+)-Pinoresinol
  • Pathway
    Angiogenesis
  • Target
    CDK
  • Recptor
    CDK;NF-κB;p53
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    487-36-5
  • Formula Weight
    358.4
  • Molecular Formula
    C20H22O6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc(cc([C@H]1OC[C@@H]2[C@@H](c(cc3)cc(OC)c3O)OC[C@H]12)cc1)c1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Among plant lignans, pinoresinol has the strongest antiinflammatory properties in human intestinal Caco-2 cells.J Nutr. 2012 Oct;142(10):1798-805.
molnova catalog
related products
  • CDKI-73

    CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM, shows cytotoxicity against a broad CLL samples with mean LD50 of 80 nM.

  • FN-1501

    FN-1501 is a potent FLT3 and CDK inhibitor (IC50s: 2.47, 0.85, 1.96, and 0.28 nM for CDK2/cyclin A, CDK4/cyclin D1, CDK6/cyclin D1 and FLT3, respectively).

  • Roscovitine

    A potent and selective CDK inhibitor with IC50 of 0.2 uM, 0.65 uM, and 0.7 uM for CDK5, Cdc2, and CDK2, respectively.