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Pinoresinol
CAS No. 487-36-5
Pinoresinol( (+)-Pinoresinol )
Catalog No. M24442 CAS No. 487-36-5
Pinoresinol has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative stress preserving pial blood flow distribution.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 160 | In Stock |
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| 10MG | 258 | In Stock |
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| 25MG | 440 | In Stock |
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| 50MG | 617 | In Stock |
|
| 100MG | 872 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NamePinoresinol
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NoteResearch use only, not for human use.
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Brief DescriptionPinoresinol has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative stress preserving pial blood flow distribution.
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DescriptionPinoresinol has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative stress preserving pial blood flow distribution; it may exert pharmacologically interesting effects via modulation of the insulin-like signalling pathway in C.elegans. Pinoresinol causes an upregulation of the CDK inhibitor p21(WAF1/Cip1) both at mRNA and protein levels, inhibits NF-kappaB and activating protein 1 (AP-1).
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In VitroPinoresinol facilitated death-inducing signaling complex formation to trigger a caspase-8-dependent apoptotic cascade activation in TRAIL-resistant glioblastoma cells.
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In Vivo——
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Synonyms(+)-Pinoresinol
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PathwayAngiogenesis
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TargetCDK
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RecptorCDK|NF-κB|p53
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Research Area——
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Indication——
Chemical Information
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CAS Number487-36-5
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Formula Weight358.4
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Molecular FormulaC20H22O6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (279.03 mM)
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SMILESCOc(cc([C@H]1OC[C@@H]2[C@@H](c(cc3)cc(OC)c3O)OC[C@H]12)cc1)c1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Among plant lignans, pinoresinol has the strongest antiinflammatory properties in human intestinal Caco-2 cells.J Nutr. 2012 Oct;142(10):1798-805.
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