Phorbol ( Phorbol )

Catalog No. M17376 CAS No. 17673-25-5

Phorbol, a plant-derived diterpene, is a tumor promoter through the activation of protein kinase C.

Purity : 98%

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Biological Information

Product Name

Phorbol
Note

Research use only, not for human use.
Brief Description

Phorbol, a plant-derived diterpene, is a tumor promoter through the activation of protein kinase C.
Description

Phorbol is a plant-derived diterpene that protmotes tumor growth through the activation of protein kinase C.
Synonyms

Phorbol
Pathway

Metabolic Enzyme/Protease
Target

Lipase
Recptor

PKC
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

17673-25-5
Formula Weight

364.43
Molecular Formula

C20H28O6
Purity

98%
Solubility

DMSO : 66.67 mg/mL 182.94 mM; H2O : ≥ 20 mg/mL 54.88 mM
SMILES

C1(=O)C(=C[C@H]2[C@@]3([C@@H](C=C(C[C@]12O)CO)[C@H]1[C@@]([C@@H]([C@H]3C)O)(C1(C)C)O)O)C
Chemical Name

(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b,9,9a-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-5H-cyclopropa[3,4]benzo[1,2-e]azulen-5-one

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Kim YI., et al. Bombyx mori hemocyte extract has anti-inflammatory effects on human phorbol myristate acetate-differentiated THP1 cells via TLR4-mediated suppression of the NF-κB sigN/Aling pathway. Mol Med Rep. 2017 Jul 26.

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