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Phorbol

CAS No. 17673-25-5

Phorbol( Phorbol )

Catalog No. M17376 CAS No. 17673-25-5

Phorbol, a plant-derived diterpene, is a tumor promoter through the activation of protein kinase C.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Phorbol
  • Note
    Research use only, not for human use.
  • Brief Description
    Phorbol, a plant-derived diterpene, is a tumor promoter through the activation of protein kinase C.
  • Description
    Phorbol is a plant-derived diterpene that protmotes tumor growth through the activation of protein kinase C.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Phorbol
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Lipase
  • Recptor
    PKC
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    17673-25-5
  • Formula Weight
    364.43
  • Molecular Formula
    C20H28O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 66.67 mg/mL 182.94 mM; H2O : ≥ 20 mg/mL 54.88 mM
  • SMILES
    C1(=O)C(=C[C@H]2[C@@]3([C@@H](C=C(C[C@]12O)CO)[C@H]1[C@@]([C@@H]([C@H]3C)O)(C1(C)C)O)O)C
  • Chemical Name
    (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b,9,9a-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-5H-cyclopropa[3,4]benzo[1,2-e]azulen-5-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kim YI., et al. Bombyx mori hemocyte extract has anti-inflammatory effects on human phorbol myristate acetate-differentiated THP?1 cells via TLR4-mediated suppression of the NF-κB sigN/Aling pathway. Mol Med Rep. 2017 Jul 26.
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