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Peimine

CAS No. 23496-41-5

Peimine( 5α-Cevane-3β,6α,20-triol | Verticine | Dihydroisoimperialine )

Catalog No. M18278 CAS No. 23496-41-5

Peimine is an inhibitor to inhibit LPS-induced production of inflammatory cytokines by blocking the MAPKs and NF-κB signaling pathway.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 43 In Stock
10MG 67 In Stock
25MG 124 In Stock
50MG 202 In Stock
100MG 321 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    Peimine
  • Note
    Research use only, not for human use.
  • Brief Description
    Peimine is an inhibitor to inhibit LPS-induced production of inflammatory cytokines by blocking the MAPKs and NF-κB signaling pathway.
  • Description
    Peimine, also known as Verticine, is a known MAPK inhibitor, as well as an inhibitor of p38, ERK and JNK phosphorylation, and NFκB activation. Peimine shows antitussive, expectorant and anti-inflammatory effects in vivo. Peimine inhibits the growth and motility of prostate cancer cells and induces apoptosis by disruption of intracellular calcium homeostasis through Ca2+ /CaMKII/JNK pathway.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    5α-Cevane-3β,6α,20-triol | Verticine | Dihydroisoimperialine
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    23496-41-5
  • Formula Weight
    431.66
  • Molecular Formula
    C27H45NO3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (115.83 mM)
  • SMILES
    CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(C6C5(CCC(C6)O)C)O)(C)O
  • Chemical Name
    (3S,4aS,5S,6aS,6bS,8aS,9S,9aS,12S,15aR,15bR,16aR,16bS)-9,12,16b-trimethyltetracosahydrobenzo[4,5]indeno[1,2-h]pyrido[1,2-b]isoquinoline-3,5,9-triol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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