PZ-2891

CAS No. 2170608-82-7

PZ-2891 ( —— )

Catalog No. M20770 CAS No. 2170608-82-7

PZ-2891 is an orally bioavailable brain penetrant pantothenate kinase (PANK) modulator(hPANK3IC50:1.3 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 43 In Stock
5MG 72 In Stock
10MG 110 In Stock
25MG 200 In Stock
50MG 332 In Stock
100MG 494 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    PZ-2891
  • Note
    Research use only not for human use.
  • Brief Description
    PZ-2891 is an orally bioavailable brain penetrant pantothenate kinase (PANK) modulator(hPANK3IC50:1.3 nM).
  • Description
    PZ-2891 is an orally bioavailable brain penetrant pantothenate kinase (PANK) modulator(hPANK3IC50:1.3 nM).
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    pantothenate kinase (PANK)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2170608-82-7
  • Formula Weight
    349.43
  • Molecular Formula
    C20H23N5O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:75 mg/mL (214.64 mM)
  • SMILES
    CC(C)c1ccc(CC(=O)N2CCN(c3ccc(C#N)nn3)CC2)cc1
  • Chemical Name
    6-(4-(2-(4-isopropylphenyl)acetyl)piperazin-1-yl)pyridazine-3-carbonitrile

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lalit Kumar Sharma et al. A therapeutic approach to pantothenate kinase associated neurodegeneration.[J]. Nature communications 2018.
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