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PTGR2-IN-22

CAS No. 349093-44-3

PTGR2-IN-22 ( —— )

Catalog No. M22891 CAS No. 349093-44-3

PTGR2-IN-22 is a potent inhibito of PTGR2r(IC50 : 0.7 μM). It increases 15-keto-PGE2-dependent PPARγ transcriptional activity in PTGR2-transfected HEK293T cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PTGR2-IN-22
  • Note
    Research use only, not for human use.
  • Brief Description
    PTGR2-IN-22 is a potent inhibito of PTGR2r(IC50 : 0.7 μM). It increases 15-keto-PGE2-dependent PPARγ transcriptional activity in PTGR2-transfected HEK293T cells.
  • Description
    PTGR2-IN-22 is a potent inhibito of PTGR2r(IC50 : 0.7 μM). It increases 15-keto-PGE2-dependent PPARγ transcriptional activity in PTGR2-transfected HEK293T cells.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PTGR2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    349093-44-3
  • Formula Weight
    310.39
  • Molecular Formula
    C19H22N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (322.18 mM; Need ultrasonic)
  • SMILES
    COC1=CC=CC=C1N2CCN(C(CC3=CC=CC=C3)=O)CC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Parker CG, et al. Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017;168(3):527-541.e29.
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