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PST-1P
CAS No. 1801769-45-8
PST-1P( —— )
Catalog No. M12745 CAS No. 1801769-45-8
PST-1P is a photoswitchable inhibitor of microtubule with EC50 of 0.7 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 100MG | Get Quote | Get Quote |
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Biological Information
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Product NamePST-1P
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NoteResearch use only, not for human use.
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Brief DescriptionPST-1P is a photoswitchable inhibitor of microtubule with EC50 of 0.7 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines.
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DescriptionPST-1P is a photoswitchable inhibitor of microtubule with EC50 of 0.7 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines; 100-fold more cytotoxic than in the dark; induces mitotic arrest and cell death in a light-dependent manner, and controls mitosis and the microtubule cytoskeleton in mammalian tissue in vivo; highly water-soluble prodrug of PST-1.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetMicrotubule/Tubulin
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RecptorMicrotubule/Tubulin
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Research Area——
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Indication——
Chemical Information
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CAS Number1801769-45-8
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Formula Weight398.308
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Molecular FormulaC16H19N2O8P
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(Z)-2-methoxy-5-((3,4,5-trimethoxyphenyl)diazenyl)phenyl dihydrogen phosphate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Borowiak M, et al. Cell. 2015 Jul 16;162(2):403-11.
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