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Home - Products - Metabolic Enzyme/Protease - Phosphatase - PP5-IN-1

PP5-IN-1

CAS No. 1022417-69-1

PP5-IN-1( —— )

Catalog No. M37297 CAS No. 1022417-69-1

PP5-IN-1 is a potent and competitive serine/threonine protein phosphatase-5 (PP5) inhibitor with potential anticancer activity that induces apoptosis in cancer cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PP5-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    PP5-IN-1 is a potent and competitive serine/threonine protein phosphatase-5 (PP5) inhibitor with potential anticancer activity that induces apoptosis in cancer cells.
  • Description
    PP5-IN-1 (Compound P053) is a competitive inhibitor of Serine/threonine protein phosphatase-5 (PP5) that binds to its catalytic domain and causes apoptosis in renal cancer.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Phosphatase
  • Recptor
    Phosphatase | Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1022417-69-1
  • Formula Weight
    342.41
  • Molecular Formula
    C18H18N2O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (292.05 mM; Ultrasonic )
  • SMILES
    O=S(=O)(NC1=CC=C(C=C1)CC=2C=CC=CC2)C=3C(=NOC3C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Elham F Ahanin, et al. Catalytic inhibitor of Protein Phosphatase 5 activates the extrinsic apoptotic pathway by disrupting complex II in kidney cancer. Cell Chem Biol. 2023 Oct 19;30(10):1223-1234.e12.?
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