PNU-112455A

CAS No. 21886-12-4

PNU-112455A ( PNU112455A )

Catalog No. M13491 CAS No. 21886-12-4

PNU-112455A is an ATP-competitive CDK2/5 inhibitor with Ki of 2 uM and 2 uM for cdk2·GST-cyclin E and cdk5·GST-p25 respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 38 Get Quote
5MG 61 Get Quote
10MG 113 Get Quote
25MG 221 Get Quote
50MG 342 Get Quote
100MG 513 Get Quote
500MG 1125 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    PNU-112455A
  • Note
    Research use only, not for human use.
  • Brief Description
    PNU-112455A is an ATP-competitive CDK2/5 inhibitor with Ki of 2 uM and 2 uM for cdk2·GST-cyclin E and cdk5·GST-p25 respectively.
  • Description
    PNU-112455A is an ATP-competitive CDK2/5 inhibitor with Ki of 2 uM and 2 uM for cdk2·GST-cyclin E and cdk5·GST-p25 respectively, shows no activity against c-c-Met, IGR-1R, and ERK2.
  • Synonyms
    PNU112455A
  • Pathway
    Angiogenesis
  • Target
    CDK
  • Recptor
    CDK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    21886-12-4
  • Formula Weight
    301.75
  • Molecular Formula
    C10H12ClN5O2S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=S(C1=CC=C(NC2=NC=NC(N)=C2)C=C1)(N)=O.[H]Cl
  • Chemical Name
    N4-(6-aminopyrimidin-4-yl)-sulfanilamide hydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Clare PM, et al. J Biol Chem. 2001 Dec 21;276(51):48292-9.
2. Monaco EA 3rd, et al. Biochem Pharmacol. 2004 May 15;67(10):1947-64.
molnova catalog
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