PLX-5622

CAS No. 1303420-67-8

PLX-5622( —— )

Catalog No. M20529 CAS No. 1303420-67-8

PLX-5622 is a highly selective brain penetrant and oral active CSF1R inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 87 In Stock
10MG 145 In Stock
25MG 292 In Stock
50MG 483 In Stock
100MG 584 In Stock
500MG 1242 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    PLX-5622
  • Note
    Research use only, not for human use.
  • Brief Description
    PLX-5622 is a highly selective brain penetrant and oral active CSF1R inhibitor.
  • Description
    PLX-5622 is a highly selective brain penetrant and oral active CSF1R inhibitor.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Tyrosine Kinase
  • Target
    CSF1R
  • Recptor
    CSF-1R
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1303420-67-8
  • Formula Weight
    395.41
  • Molecular Formula
    C21H19F2N5O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:79 mg/mL (199.79 mM)
  • SMILES
    COc1ncc(F)cc1CNc1ccc(Cc2c[nH]c3ncc(C)cc23)c(F)n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Rosin JM Vora SR Kurrasch DM.Depletion of embryonic microglia using the CSF1R inhibitor PLX5622 has adverse sex-specific effects on mice including accelerated weight gain hyperactivity and anxiolytic-like behaviour[J].Brain Behav Immun. 2018 Oct;73:682-697.
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