PL265
CAS No. 1206514-50-2
PL265( PL-265 | PL 265 )
Catalog No. M10755 CAS No. 1206514-50-2
PL265 (PL-265) is a dual enkephalinase inhibitor, alleviate corneal pain and inflammation in vivo.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
100MG | Get Quote | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NamePL265
-
NoteResearch use only, not for human use.
-
Brief DescriptionPL265 (PL-265) is a dual enkephalinase inhibitor, alleviate corneal pain and inflammation in vivo.
-
DescriptionPL265 (PL-265) is a dual enkephalinase inhibitor, alleviate corneal pain and inflammation in vivo.Pain Phase 1 Clinical.
-
In Vitro——
-
In Vivo——
-
SynonymsPL-265 | PL 265
-
PathwayMetabolic Enzyme/Protease
-
TargetNeprilysin
-
RecptorNeprilysin
-
Research AreaNeurological Disease
-
IndicationPain
Chemical Information
-
CAS Number1206514-50-2
-
Formula Weight576.583
-
Molecular FormulaC28H37N2O9P
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCC(C)C(=O)OC(C)OC(=O)NC(C)P(=O)(CC(CC1=CC=C(C=C1)C2=CC=CC=C2)C(=O)NC(C)C(=O)O)O
-
Chemical Name((2S)-3-([1,1'-biphenyl]-4-yl)-2-((hydroxy((1R)-1-(((1-(isobutyryloxy)ethoxy)carbonyl)amino)ethyl)phosphoryl)methyl)propanoyl)-L-alanine
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Bonnard E, et al. Pharmacol Res Perspect. 2015 Mar;3(2):e00116.
molnova catalog
related products
-
PL265
PL265 (PL-265) is a dual enkephalinase inhibitor, alleviate corneal pain and inflammation in vivo.
-
LHW090-A7
LHW090-A7 is an neutral endopeptidase (NEP) inhibitor, and an enzyme responsible for the metabolic inactivation of enkephalins.
-
LCZ-696
A novel single molecule comprising molecular moieties of valsartan and NEP inhibitor prodrug AHU377.