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PIK-294
CAS No. 900185-02-6
PIK-294 ( PIK294; PIK 294; PIK-294 )
Catalog No. M16469 CAS No. 900185-02-6
A highly potent, selective p110δ inhibitor with IC50 of 10 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 36 | In Stock |
|
| 5MG | 58 | In Stock |
|
| 10MG | 102 | In Stock |
|
| 25MG | 162 | In Stock |
|
| 50MG | 259 | In Stock |
|
| 100MG | 405 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePIK-294
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NoteResearch use only, not for human use.
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Brief DescriptionA highly potent, selective p110δ inhibitor with IC50 of 10 nM.
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DescriptionA highly potent, selective p110δ inhibitor with IC50 of 10 nM; shows 1000-, 49- and 16-fold less potent to PI3Kα/β/γ.
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SynonymsPIK294; PIK 294; PIK-294
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PathwayPI3K/Akt/mTOR signaling
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TargetPI3K
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Recptorp110α;p110β;p110γ;p110δ
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number900185-02-6
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Formula Weight489.53
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Molecular FormulaC28H23N7O2
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 40 mg/mL
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SMILESO=C1N(C2=CC=CC=C2C)C(CN3N=C(C4=CC=CC(O)=C4)C5=C(N)N=CN=C53)=NC6=C1C(C)=CC=C6
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Chemical Name4(3H)-Quinazolinone, 2-[[4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-5-methyl-3-(2-methylphenyl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Knight ZA, et al. Cell. 2006 May 19;125(4):733-47.
2. Martin KJ, et al. PLoS One. 2015 Feb 6;10(2):e0116250.
2. Martin KJ, et al. PLoS One. 2015 Feb 6;10(2):e0116250.
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