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PI3K-IN-1
CAS No. 1349796-36-6
PI3K-IN-1 ( SAR245409; Voxtalisib )
Catalog No. M11414 CAS No. 1349796-36-6
PI3K-IN-1 is a potent inhibitor of PI3K.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 39 | In Stock |
|
| 5MG | 61 | In Stock |
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| 10MG | 105 | In Stock |
|
| 25MG | 208 | In Stock |
|
| 50MG | 295 | In Stock |
|
| 100MG | 478 | In Stock |
|
| 500MG | 1062 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePI3K-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionPI3K-IN-1 is a potent inhibitor of PI3K.
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DescriptionPI3K-IN-1 is a potent inhibitor of PI3K, extracted from patent WO2012103524 A2 and WO2013147649 A2.
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SynonymsSAR245409; Voxtalisib
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PathwayPI3K/Akt/mTOR signaling
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TargetPI3K
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RecptorDNA-PK;PI3Kα;PI3Kβ;PI3Kγ;PI3Kδ
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1349796-36-6
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Formula Weight599.66
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Molecular FormulaC31H29N5O6S
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Purity>98% (HPLC)
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SolubilityDMSO: 27.5 mg/mL
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SMILESO=C(NC1=CC=C(S(=O)(NC2=NC3=CC=CC=C3N=C2NC4=CC(OC)=CC(OC)=C4)=O)C=C1)C5=CC=C(C)C(OC)=C5
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Chemical NameN-(4-(N-(3-((3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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Idelalisib
Idelalisib is a selective inhibitor of p110δ(IC50 : 2.5 nM; in cell-free assays); shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ, and 400- to 4000-fold more selectivity to p110δ than C2β, hVPS34, DNA-PK and mTOR.
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GDC-0326
A potent, selective, orally available PI3Kα inhibitor with Ki of 0.2 nM; displays 133, 20 and 33-fold selectivity over PI3Kβ, PI3Kδ and PI3Kγ, respectively.
