PGD2-inhibitor

Research use only, not for human use.

MDK66671 is a prostaglandin D2（PGD2) inhibitor. MDK66671 has CAS#885066-67-1, in which the last five digit was used in its name.

MDK66671 is a prostaglandin D2（PGD2) inhibitor. MDK66671 has CAS#885066-67-1, in which the last five digit was used in its name.

Prostaglandin D2 (PGD2) is a major inflammatory mediator implicated in asthma and allergic rhinitis. It is largely produced as the major cyclooxygenase metabolite upon allergen-provoked degranulation from mast cells. Blockage of PGD2 using DP antagonists has been shown to be effective at alleviating the symptoms of allergic rhinitis in multiple species and more specifically has been shown to inhibit the antigen-induced nasal congestion.

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MDK66671 | MDK-66671 MDK 66671

Others

Other Targets

PGD2(DP)

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885066-67-1

460.35

C23H23Cl2N3O3

>98% (HPLC)

DMSO : ≥ 25 mg/mL; 54.31 mM

COc2nc(cc(NCCc1ccc(Cl)cc1Cl)n2)c3cccc(c3)C(C)(C)C(=O)O

2-(3-(6-((2,4-dichlorophenethyl)amino)-2-methoxypyrimidin-4-yl)phenyl)-2-methylpropanoic acid

(-20℃)

With Ice Pack

≥ 2 years