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Hydroxy-PEG10-acid

CAS No. 2375611-66-6

Hydroxy-PEG10-acid( HO-PEG10-CH2CH2COOH )

Catalog No. M26966 CAS No. 2375611-66-6

Hydroxy-PEG10-acid is a PEG-based PROTAC linker that can be used to synthesize PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Hydroxy-PEG10-acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Hydroxy-PEG10-acid is a PEG-based PROTAC linker that can be used to synthesize PROTACs.
  • Description
    Hydroxy-PEG10-acid is a PEG-based PROTAC linker that can be used to synthesize PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    HO-PEG10-CH2CH2COOH
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PIP5K1α
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2375611-66-6
  • Formula Weight
    530.608
  • Molecular Formula
    C23H46O13
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Sarwar M, et al. Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes MDV3100 resistance in prostate cancer cells. Oncotarget. 2016 Sep 27;7(39):63065-63081.
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