Hydroxy-PEG10-acid( HO-PEG10-CH2CH2COOH )

Catalog No. M26966 CAS No. 2375611-66-6

Hydroxy-PEG10-acid is a PEG-based PROTAC linker that can be used to synthesize PROTACs.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Hydroxy-PEG10-acid
Note

Research use only, not for human use.
Brief Description

Hydroxy-PEG10-acid is a PEG-based PROTAC linker that can be used to synthesize PROTACs.
Description

Hydroxy-PEG10-acid is a PEG-based PROTAC linker that can be used to synthesize PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vivo

——
Synonyms

HO-PEG10-CH2CH2COOH
Pathway

Others
Target

Other Targets
Recptor

PIP5K1α
Research Area

——
Indication

——

Chemical Information

CAS Number

2375611-66-6
Formula Weight

530.608
Molecular Formula

C23H46O13
Purity

>98% (HPLC)
Solubility

——
SMILES

OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Sarwar M, et al. Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes MDV3100 resistance in prostate cancer cells. Oncotarget. 2016 Sep 27;7(39):63065-63081.

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