PFK-015

CAS No. 4382-63-2

PFK-015 ( PFK015; PFK 015; PFK015. )

Catalog No. M18553 CAS No. 4382-63-2

PFK-015 is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 47 In Stock
10MG 73 In Stock
25MG 146 In Stock
50MG 267 In Stock
100MG 397 In Stock
200MG 551 In Stock
500MG 878 In Stock
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Biological Information

  • Product Name
    PFK-015
  • Note
    Research use only, not for human use.
  • Brief Description
    PFK-015 is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).
  • Description
    PFK-015 is a potent inhibitor of PFKFB3. The preliminary results in a U87GM xenograft model have shown that PFK-015 has comparable activity to Temozolomide. PFK-015 inhibits glucoseuptake by tumors.
  • Synonyms
    PFK015; PFK 015; PFK015.
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PFKFB3
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    4382-63-2
  • Formula Weight
    260.29
  • Molecular Formula
    C17H12N2O
  • Purity
    98%
  • Solubility
    DMSO : 25.2 mg/mL 96.82 mM; H2O : < 0.1 mg/mL
  • SMILES
    C(=O)(/C=C/c1nc2c(cc1)cccc2)c1ccncc1
  • Chemical Name
    (E)-3-(pyridin-3-yl)-1-(quinolin-3-yl)prop-2-en-1-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Clem BF, et al. Mol Y Ther. 2013, 12(8), 1461-1470.
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