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PFK-015
CAS No. 4382-63-2
PFK-015 ( PFK015; PFK 015; PFK015. )
Catalog No. M18553 CAS No. 4382-63-2
PFK-015 is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 47 | In Stock |
|
| 10MG | 73 | In Stock |
|
| 25MG | 146 | In Stock |
|
| 50MG | 267 | In Stock |
|
| 100MG | 397 | In Stock |
|
| 200MG | 551 | In Stock |
|
| 500MG | 878 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePFK-015
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NoteResearch use only, not for human use.
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Brief DescriptionPFK-015 is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).
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DescriptionPFK-015 is a potent inhibitor of PFKFB3. The preliminary results in a U87GM xenograft model have shown that PFK-015 has comparable activity to Temozolomide. PFK-015 inhibits glucoseuptake by tumors.
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SynonymsPFK015; PFK 015; PFK015.
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PathwayOthers
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TargetOther Targets
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RecptorPFKFB3
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number4382-63-2
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Formula Weight260.29
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Molecular FormulaC17H12N2O
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Purity98%
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SolubilityDMSO : 25.2 mg/mL 96.82 mM; H2O : < 0.1 mg/mL
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SMILESC(=O)(/C=C/c1nc2c(cc1)cccc2)c1ccncc1
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Chemical Name(E)-3-(pyridin-3-yl)-1-(quinolin-3-yl)prop-2-en-1-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Clem BF, et al. Mol Y Ther. 2013, 12(8), 1461-1470.
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