N-Isovalerylglycine

Research use only not for human use.

Isovalerylglycine (IVG) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation.

Isovalerylglycine (IVG) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase which is an enzyme that catalyzes the chemical reaction: acyl-CoA + glycine < -- > CoA + N-acylglycine. Isovalerylglycine is a byproduct of the catabolism of the amino acid leucine. Accumulation of isovalerylglycine occurs in Isovaleric Acidemia (IVA).

N-Isovaleroylglycine;Isovaleroylglycine

Others

Other Targets

Others

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16284-60-9

159.18

C7H13NO3

>98% (HPLC)

DMSO: 5 mg/mL;Methanol: 2 mg/mL

CC(C)CC(=O)NCC(O)=O

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(-20℃)

With Ice Pack

≥ 2 years