PF-CBP1
CAS No. 1962928-21-7
PF-CBP1 ( PF CBP1 )
Catalog No. M13078 CAS No. 1962928-21-7
A potent, highly selective CBP/p300 bromodomains inhibitor with IC50 of 125 nM and 363 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 45 | In Stock |
|
5MG | 57 | In Stock |
|
10MG | 99 | In Stock |
|
25MG | 194 | In Stock |
|
50MG | 352 | In Stock |
|
100MG | 524 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePF-CBP1
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent, highly selective CBP/p300 bromodomains inhibitor with IC50 of 125 nM and 363 nM, respectively.
-
DescriptionA potent, highly selective CBP/p300 bromodomains inhibitor with IC50 of 125 nM and 363 nM, respectively; displays >100-fold selectivity for the bromodomain of CBP over those of BRD4 and a panel of other proteins; reduces the expression of inflammatory cytokines by LPS-stimulated primary macrophages, also suppresses the expression of RGS4 in primary cortical neurons.
-
SynonymsPF CBP1
-
PathwayChromatin/Epigenetic
-
TargetBromodomain
-
RecptorCREB
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1962928-21-7
-
Formula Weight488.60
-
Molecular FormulaC29H36N4O3
-
Purity>98% (HPLC)
-
SolubilityDMSO: 100 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
-
SMILESCCCOC1=CC=C(C=C1)CCC2=NC3=C(N2CCN4CCOCC4)C=CC(=C3)C5=C(ON=C5C)C
-
Chemical Name4-(2-(5-(3,5-dimethylisoxazol-4-yl)-2-(4-propoxyphenethyl)-1H-benzo[d]imidazol-1-yl)ethyl)morpholine
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Chekler EL, et al. Chem Biol. 2015 Dec 17;22(12):1588-96.
molnova catalog
related products
-
BAZ2-ICR
BAZ2-ICR is a potent, selective and cell-active inhibitor of BAZ2A and BAZ2B bromodomains.
-
GNE-207
GNE-207 (GNE207) is a novel potent, selective, orally active CBP/p300 bromodomain with IC50 of 1.0 nM.
-
SJ830599
SJ830599 is a modest selective BRD2-BD2 inhibitor with IC50 of 0.61 uM, 3.3-fold selectivity over BRD2-BD1.