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PF-562271
CAS No. 717907-75-0
PF-562271 ( —— )
Catalog No. M15746 CAS No. 717907-75-0
PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 70 | In Stock |
|
| 5MG | 116 | In Stock |
|
| 10MG | 146 | In Stock |
|
| 25MG | 246 | In Stock |
|
| 50MG | 357 | In Stock |
|
| 100MG | 537 | In Stock |
|
| 500MG | 1134 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePF-562271
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NoteResearch use only, not for human use.
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Brief DescriptionPF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays.
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DescriptionPF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
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Synonyms——
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PathwayAngiogenesis
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TargetCDK
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RecptorCDK1/CyclinB; CDK2/CyclinE; CDK3/CyclinE; FAK; PYK2
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Research AreaCancer
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IndicationSolid Tumors
Chemical Information
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CAS Number717907-75-0
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Formula Weight507.49
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Molecular FormulaC21H20F3N7O3S
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Purity>98%(HPLC)
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SolubilityDMSO: 100 mg/mL warmed (197.04 mM)
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SMILESCN(S(C)(=O)=O)C1=C(CNC2=C(C(F)(F)F)C=NC(NC3=CC=C(NC(C4)=O)C4=C3)=N2)C=CC=N1.OS(C5=CC=CC=C5)(=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Roberts WG, et al. Y Res, 2008, 68(6), 1935-1944.
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