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PF-06651481-00
CAS No. 1391063-17-4
PF-06651481-00( —— )
Catalog No. M34375 CAS No. 1391063-17-4
PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 53 | Get Quote |
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| 5MG | 77 | Get Quote |
|
| 10MG | 123 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NamePF-06651481-00
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NoteResearch use only, not for human use.
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Brief DescriptionPF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.
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DescriptionBosutinib isomer is a ligand or inhibitor with high binding affinity for both Wee1 and Wee2, with Kd values of 43.7 ± 10.0 and 4.7 ± 2.3 nM, respectively.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetBcr-Abl
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RecptorBcr-Abl
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Research Area——
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Indication——
Chemical Information
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CAS Number1391063-17-4
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Formula Weight530.45
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Molecular FormulaC26H29Cl2N5O3
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Purity>98% (HPLC)
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Solubility——
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SMILESN(C=1C2=C(C=C(OCCCN3CCN(C)CC3)C(OC)=C2)N=CC1C#N)C4=CC(Cl)=C(OC)C(Cl)=C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhu JY, et al. Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors. J Med Chem. 2017 Sep 28;60(18):7863-7875.?
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