Cart
sales@molnova.com
PF-06424439
CAS No. 1469284-78-3
PF-06424439 ( —— )
Catalog No. M23628 CAS No. 1469284-78-3
PF-06424439 is an oral and selective inhibitor of imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) (IC50 of 14 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 963 | In Stock |
|
| 50MG | 1962 | In Stock |
|
| 100MG | 2520 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePF-06424439
-
NoteResearch use only, not for human use.
-
Brief DescriptionPF-06424439 is an oral and selective inhibitor of imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) (IC50 of 14 nM).
-
DescriptionPF-06424439 is an oral and selective inhibitor of imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) (IC50 of 14 nM).
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetTransferase
-
RecptorDGAT2
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1469284-78-3
-
Formula Weight439.9
-
Molecular FormulaC22H26ClN7O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C([C@H](CCC1)CN1c(cc1)nc2c1nc(C1(CC1)n1ncc(Cl)c1)[nH]2)N1CCCC1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Futatsugi K, et al. Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2). J Med Chem. 2015 Sep 24;58(18):7173-85.
molnova catalog
related products
-
histidine
Histidine is a semi-essential amino acid (children should obtain it from food) needed in humans for growth and tissue repair.
-
FK866
FK866 (APO866, Daporinad) effectively inhibits nicotinamide phosphoribosyltransferase (NMPRTase) with IC50 of 0.09 nM in a cell-free assay. Phase 1/2.
-
Opicapone
Opicapone reduces the ATP content of the cells (IC50: 98 μM).
