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Eletriptan

CAS No. 143322-58-1

Eletriptan ( UK 116044 )

Catalog No. M11842 CAS No. 143322-58-1

Eletriptan (UK 116044) is a potent, selective, and orally active 5-HT1B/1D receptor agonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Eletriptan
  • Note
    Research use only, not for human use.
  • Brief Description
    Eletriptan (UK 116044) is a potent, selective, and orally active 5-HT1B/1D receptor agonist.
  • Description
    Eletriptan (UK 116044) is a potent, selective, and orally active 5-HT1B/1D receptor agonist; significantly increases occluded wedge pressure and mean pulmonary artery pressure in vivo, with no significant coronary artery constriction, and obstructive coronary artery disease; displays antimigraine activity.Migraine Approved
  • Synonyms
    UK 116044
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT Receptor
  • Research Area
    Neurological Disease
  • Indication
    Migraine

Chemical Information

  • CAS Number
    143322-58-1
  • Formula Weight
    382.52
  • Molecular Formula
    C22H26N2O2S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CN1CCC[C@@H]1Cc2c[nH]c3c2cc(cc3)CCS(=O)(=O)c4ccccc4
  • Chemical Name
    3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Napier C, et al. Eur J Pharmacol. 1999 Mar 5;368(2-3):259-68.
2. Gupta P, et al. Eur J Pharmacol. 1999 Feb 19;367(2-3):283-90.
3. Muir DF, et al. Clin Pharmacol Ther. 1999 Jul;66(1):85-90.
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