PF-00217830( —— )

Catalog No. M34016 CAS No. 846032-02-8

PF-00217830 is a serotonin 1A receptor agonist, dopamine D2 receptor agonist, and serotonin 2A receptor antagonist.PF-00217830 may be used in the study of schizophrenia.

Purity : >98% (HPLC)

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Biological Information

Product Name

PF-00217830
Note

Research use only, not for human use.
Brief Description

PF-00217830 is a serotonin 1A receptor agonist, dopamine D2 receptor agonist, and serotonin 2A receptor antagonist.PF-00217830 may be used in the study of schizophrenia.
Description

F-00217830 is an agonist ofDopamine D2 receptor. PF-00217830 inhibits of spontaneous locomotor activity and 2,5-dimethoxy-4-iodoamphetamine-induced head twitches in rats.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Dopamine Receptor
Recptor

Dopamine Receptor | Serotonin Transporter
Research Area

——
Indication

——

Chemical Information

CAS Number

846032-02-8
Formula Weight

430.54
Molecular Formula

C26H30N4O2
Purity

>98% (HPLC)
Solubility

——
SMILES

C(CCCOC=1NC=2C(=CC1)CCC(=O)N2)N3CCN(C=4C5=C(C=CC4)C=CC=C5)CC3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Johnson DS, et al. Discovery of PF-00217830: aryl piperazine napthyridinones as D2 partial agonists for schizophrenia and bipolar disorder. Bioorg Med Chem Lett. 2011;21(9):2621-2625.?

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