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PERK-IN-4
CAS No. 1337531-89-1
PERK-IN-4( —— )
Catalog No. M35065 CAS No. 1337531-89-1
PERK-IN-4 is a potent and selective PERK inhibitor with an IC50 value of 0.3 nM, used in the study of cancer and neurological disorders.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 90 | In Stock |
|
| 5MG | 140 | In Stock |
|
| 10MG | 217 | In Stock |
|
| 25MG | 394 | In Stock |
|
| 50MG | 585 | In Stock |
|
| 100MG | 798 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePERK-IN-4
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NoteResearch use only, not for human use.
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Brief DescriptionPERK-IN-4 is a potent and selective PERK inhibitor with an IC50 value of 0.3 nM, used in the study of cancer and neurological disorders.
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DescriptionPERK-IN-4 is a potent and selective PERK (protein kinase R (PKR)-like endoplasmic reticulum kinase) inhibitor with an IC 50 of 0.3 nM. PERK is activated in response to a variety of endoplasmic reticulum stresses implicated in numerous disease states.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetPERK
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RecptorPERK
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Research Area——
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Indication——
Chemical Information
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CAS Number1337531-89-1
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Formula Weight469.43
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Molecular FormulaC24H19F4N5O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 20.83 mg/mL (44.37 mM; Ultrasonic )
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SMILESCn1cc(-c2ccc3N(CCc3c2)C(=O)Cc2cc(F)cc(c2)C(F)(F)F)c2c(N)ncnc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Axten JM, et al. Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulu?
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