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PD-1-IN-1

CAS No. 1673534-76-3

PD-1-IN-1( CA-170 | CA-170 | CA-170 | AUPM 170 | AUPM-170 | AUPM170 | PD-1-IN-1 )

Catalog No. M12554 CAS No. 1673534-76-3

PD-1-IN-1 is a small molecule inhibitor of programmed cell dealth-1 (PD-1).

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    PD-1-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    PD-1-IN-1 is a small molecule inhibitor of programmed cell dealth-1 (PD-1).
  • Description
    PD-1-IN-1 is a small molecule inhibitor of programmed cell dealth-1 (PD-1) extracted from patent WO 2015033299 A1, compound example 4.
  • In Vitro
    CA-170 exhibits potent functional activity in rescuing T-cell proliferation and effector functions, while showing selectivity against other immune checkpoint proteins as well as in a broad panel of receptors and enzymes.
  • In Vivo
    ——
  • Synonyms
    CA-170 | CA-170 | CA-170 | AUPM 170 | AUPM-170 | AUPM170 | PD-1-IN-1
  • Pathway
    Immunology/Inflammation
  • Target
    PD-1/PD-L1
  • Recptor
    PD-1/PD-L1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1673534-76-3
  • Formula Weight
    360.3232
  • Molecular Formula
    C12H20N6O7
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 28.5 mg/mL
  • SMILES
    OC([C@H]([C@@H](O)C)NC(N[C@@H](CC(N)=O)C1=NC([C@@H](CO)N)=NO1)=O)=O
  • Chemical Name
    L-Threonine, N-[[[(1S)-3-amino-1-[3-[(1R)-1-amino-2-hydroxyethyl]-1,2,4-oxadiazol-5-yl]-3-oxopropyl]amino]carbonyl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Patent WO 2015033299 A1.
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