PA3552-IN-1( —— )

Catalog No. M36072 CAS No. 1008121-12-7

PA3552-IN-1 is an antibiotic adjuvant that can reduce the expression of PA3552 and restore the sensitivity of MDR Pseudomonas aeruginosa DK2 strain to Polymyxin B.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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10MG	92	Get Quote
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Biological Information

Product Name

PA3552-IN-1
Note

Research use only, not for human use.
Brief Description

PA3552-IN-1 is an antibiotic adjuvant that can reduce the expression of PA3552 and restore the sensitivity of MDR Pseudomonas aeruginosa DK2 strain to Polymyxin B.
Description

PA3552-IN-1 (compound 15) is an antibiotic adjuvant that restores sensitivity of MDR P. aeruginosa DK2 strain to Polymyxin B. PA3552-IN-1 can reduce PA3552 expression.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

1008121-12-7
Formula Weight

310.67
Molecular Formula

C13H8ClFN2O4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : ≥ 13.89 mg/mL (44.71 mM)
SMILES

Oc1ccc(F)cc1C(=O)Nc1ccc(cc1Cl)[N+]([O-])=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Lu T, et, al. Novel niclosamide-derived adjuvants elevating the efficacy of polymyxin B against MDR Pseudomonas aeruginosa DK2. Eur J Med Chem. 2022 Jun 5;236:114318.?

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