PA3552-IN-1

CAS No. 1008121-12-7

PA3552-IN-1( —— )

Catalog No. M36072 CAS No. 1008121-12-7

PA3552-IN-1 is an antibiotic adjuvant that can reduce the expression of PA3552 and restore the sensitivity of MDR Pseudomonas aeruginosa DK2 strain to Polymyxin B.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 52 Get Quote
10MG 92 Get Quote
25MG 182 Get Quote
50MG 302 Get Quote
100MG 446 Get Quote
500MG 963 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    PA3552-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    PA3552-IN-1 is an antibiotic adjuvant that can reduce the expression of PA3552 and restore the sensitivity of MDR Pseudomonas aeruginosa DK2 strain to Polymyxin B.
  • Description
    PA3552-IN-1 (compound 15) is an antibiotic adjuvant that restores sensitivity of MDR P. aeruginosa DK2 strain to Polymyxin B. PA3552-IN-1 can reduce PA3552 expression.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1008121-12-7
  • Formula Weight
    310.67
  • Molecular Formula
    C13H8ClFN2O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 13.89 mg/mL (44.71 mM)
  • SMILES
    Oc1ccc(F)cc1C(=O)Nc1ccc(cc1Cl)[N+]([O-])=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lu T, et, al. Novel niclosamide-derived adjuvants elevating the efficacy of polymyxin B against MDR Pseudomonas aeruginosa DK2. Eur J Med Chem. 2022 Jun 5;236:114318.?
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