P7C3

CAS No. 301353-96-8

P7C3 ( P7C3 )

Catalog No. M13940 CAS No. 301353-96-8

The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 39 In Stock
10MG 63 In Stock
25MG 120 In Stock
50MG 215 In Stock
100MG 357 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    P7C3
  • Note
    Research use only, not for human use.
  • Brief Description
    The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration.
  • Description
    The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration. We now show that P7C3 molecules additionally preserve axonal integrity after injury, before neuronal cell death occurs, in a rodent model of blast-mediated traumatic brain injury (TBI). This protective quality may be linked to the ability of P7C3 molecules to activate nicotinamide phosphoribosyltransferase, the rate-limiting enzyme in nicotinamide adenine dinucleotide salvage.
  • Synonyms
    P7C3
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    nicotinamide phosphoribosyltransferase
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    301353-96-8
  • Formula Weight
    474.19
  • Molecular Formula
    C21H18Br2N2O
  • Purity
    >98%(HPLC)
  • Solubility
    Soluble in DMSO
  • SMILES
    OC(CNC1=CC=CC=C1)CN2C3=C(C4=C2C=CC(Br)=C4)C=C(Br)C=C3
  • Chemical Name
    1-(3,6-dibromo-9H-carbazol-9-yl)-3-(phenylamino)propan-2-ol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Yin TC, et al. Cell Rep. 2014 Sep 25;8(6): 1731-40.
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