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CCG 50014
CAS No. 883050-24-6
CCG 50014( CCG-50014 | CCG 50014 | CCG50014 )
Catalog No. M17641 CAS No. 883050-24-6
CCG 50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 50 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 46 | In Stock |
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| 10MG | 77 | In Stock |
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| 25MG | 155 | In Stock |
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| 50MG | 245 | In Stock |
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| 100MG | 390 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCCG 50014
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NoteResearch use only, not for human use.
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Brief DescriptionCCG 50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.
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DescriptionCCG-50014 is a potent small molecule inhibitor of regulator of G-protein signaling protein 4 (RGS4).
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In Vitro——
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In VivoCCG50014 (10, 30, or 100 nM) attenuates the nociceptive responses during the late phase in a dose-dependent manner.
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SynonymsCCG-50014 | CCG 50014 | CCG50014
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PathwayOthers
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TargetOther Targets
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RecptorRGS16| RGS19| RGS4| RGS8
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number883050-24-6
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Formula Weight316.35
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Molecular FormulaC16H13FN2O2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 62.5 mg/mL (197.57 mM)
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SMILESCC1=CC=C(C=C1)N1SC(=O)N(CC2=CC=C(F)C=C2)C1=O
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Chemical Name4-[(4-fluorophenyl)methyl]-2-(4-methylphenyl)-1,2,4-thiadiazolidine-3,5-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Epimagnolin A
Epimagnolin A is a lignan obtained from the flower buds of Magnolia fargesii, which is traditionally used in Asian medicine for treating headache and nasal congestion.?A herbal compound fargesin obtained from M. fargesii, has exerted anti-inflammatory effects in human monocytic THP-1 cells in the previous study.?it was demonstrated that epimagnolin A reduced phorbol-12-myristate-13-acetate (PMA)-induced IL-6 promoter activity and IL-6 production in human monocytic THP-1 cells.?
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Norrubrofusarin
Norrubrofusarin (Didemethylasperxanthone) is a natural product that can be obtained by demethylation of the metabolite (Compound III) of Aspergillus nige.
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(-)-Syringaresinol 4...
(-)-Syringaresinol inhibits the proliferation of human promyelocytic HL-6 cells through G(1) arrest and induction of apoptosis, may be a potential chemotherapeutic agent for the treatment of cancer.
