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P-SCN-Bn-DOTA

CAS No. 127985-74-4

P-SCN-Bn-DOTA( —— )

Catalog No. M35058 CAS No. 127985-74-4

p-SCN-Bn-DOTA is a chelator that simultaneously binds radionuclides and links monoclonal antibodies.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    P-SCN-Bn-DOTA
  • Note
    Research use only, not for human use.
  • Brief Description
    p-SCN-Bn-DOTA is a chelator that simultaneously binds radionuclides and links monoclonal antibodies.
  • Description
    p-SCN-Bn-DOTA is a bifunctional chelating agent. p-SCN-Bn-DOTA can simultaneously chelate radionuclides and link monoclonal antibody for radioimmunoresearch of tumor.
  • In Vitro
    p-SCN-Bn-DOTA is complexed with 5 different metal ions: In(III), Y(III), Lu(III), Gd(III) and Cu(II).
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    127985-74-4
  • Formula Weight
    551.61
  • Molecular Formula
    C24H33N5O8S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 20.83 mg/mL (37.76 mM; Ultrasonic (<60°C)
  • SMILES
    OC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)C(Cc2ccc(cc2)N=C=S)CN(CC(O)=O)CC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Vera DRB, et, al. Preclinical evaluation of (177)lu-nimotuzumab: a potential tool for radioimmunotherapy of epidermal growth factor receptor-overexpressing tumors. Cancer Biother Radiopharm. 2011 Jun;26(3):287-97.?
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