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P-2281
CAS No. 1112994-35-0
P-2281( —— )
Catalog No. M34370 CAS No. 1112994-35-0
P-2281 is an mTOR inhibitor with anticancer and anti-inflammatory properties.P-2281 inhibits dextran sulfate sodium (DSS)-induced colitis by suppressing T-cell function and is effective in a mouse model of human colitis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 240 | Get Quote |
|
| 5MG | 376 | Get Quote |
|
| 10MG | 541 | Get Quote |
|
| 25MG | 899 | Get Quote |
|
| 50MG | 1187 | Get Quote |
|
| 100MG | 1593 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameP-2281
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NoteResearch use only, not for human use.
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Brief DescriptionP-2281 is an mTOR inhibitor with anticancer and anti-inflammatory properties.P-2281 inhibits dextran sulfate sodium (DSS)-induced colitis by suppressing T-cell function and is effective in a mouse model of human colitis.
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DescriptionP-2281 is a mTOR inhibitor with anticancer and anti-inflammatory efficacies. P-2281 suppresses dextran sulfate sodium (DSS)-induced colitis by inhibiting T cell function and is efficacious in a murine model of human colitis.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayPI3K/Akt/mTOR signaling
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TargetmTOR
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RecptormTOR
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Research Area——
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Indication——
Chemical Information
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CAS Number1112994-35-0
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Formula Weight209.63
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Molecular FormulaC9H8ClN3O
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Purity>98% (HPLC)
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Solubility——
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SMILESN(C(C(C)Cl)=O)C=1C=CC(C#N)=NC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Mandar R Bhonde, et al. A novel mTOR inhibitor is efficacious in a murine model of colitis. Am J Physiol Gastrointest Liver Physiol. 2008 Dec;295(6):G1237-45. ?
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