Ozenoxacin

Research use only, not for human use.

Ozenoxacin is a quinolone antibacterial. It shows potent activities against the main microorganisms isolated from soft tissue and skin infections.

Ozenoxacin is a quinolone antibacterial. It shows potent activities against the main microorganisms isolated from soft tissue and skin infections.(In Vitro):Ozenoxacin (OZN) shows potent antibacterial activities against clinical isolates of Gram-positive microorganisms, with MICs ranging from 0.008 to 4 mg/L. Ozenoxacin shows good activities against strains of MRSA, MSSA, MSSE, and MRSE with 2, 3, or 4 mutations in the gyrA and grlA (parC) genes. Ozenoxacin inhibits MSSA strains and S. agalactiae strains, with the rates of resistance of >10?10 and 5.3 × 10?10, respectively. The maximum MIC value for mutant strains is 8 mg/L for ozenoxacin.

Ozenoxacin (OZN) shows potent antibacterial activities against clinical isolates of Gram-positive microorganisms, with MICs ranging from 0.008 to 4 mg/L. Ozenoxacin shows good activities against strains of MRSA, MSSA, MSSE, and MRSE with 2, 3, or 4 mutations in the gyrA and grlA (parC) genes. Ozenoxacin inhibits MSSA strains and S. agalactiae strains, with the rates of resistance of >10?10 and 5.3 × 10?10, respectively. The maximum MIC value for mutant strains is 8 mg/L for ozenoxacin.

——

T-3912

GPCR/G Protein

Antibacterial

Bacterial

Infection

Impetigo

245765-41-7

363.41

C21H21N3O3

>98% (HPLC)

DMSO: 5 mg/mL (13.76 mM; Need ultrasonic and warming)

O=C(C1=CN(C2CC2)C3=C(C=CC(C4=CC(C)=C(NC)N=C4)=C3C)C1=O)O

1-cyclopropyl-8-methyl-7-(5-methyl-6-(methylamino)pyridin-3-yl)-4-oxo-14-dihydroquinoline-3-carboxylic acid

(-20℃)

With Ice Pack

≥ 2 years