Vaborbactam ( RPX-7009 )

Catalog No. M11479 CAS No. 1360457-46-0

A serine β-lactamase inhibitor that notably restores the activity of carbapenems against KPC-producing strains.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Vaborbactam
Note

Research use only, not for human use.
Brief Description

A serine β-lactamase inhibitor that notably restores the activity of carbapenems against KPC-producing strains.
Description

A serine β-lactamase inhibitor that notably restores the activity of carbapenems against KPC-producing strains; restores meropenem activity for 72.7 to 98.1% of CPE isolates at ≤2 ug/ml; showes no antibacterial activity alone (MICs, >64 ug/ml).Bacterial Infection Approved
Synonyms

RPX-7009
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

Infection
Indication

Bacterial Infection

Chemical Information

CAS Number

1360457-46-0
Formula Weight

297.14
Molecular Formula

C12H16BNO5S
Purity

>98% (HPLC)
Solubility

DMSO: 10 mM
SMILES

O=C(O)C[C@@H]1CC[C@H](NC(CC2=CC=CS2)=O)B(O)O1
Chemical Name

1,2-Oxaborinane-6-acetic acid, 2-hydroxy-3-[[2-(2-thienyl)acetyl]amino]-, (3R,6S)-

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Castanheira M, et al. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5454-8.
2. Hecker SJ, et al. J Med Chem. 2015 May 14;58(9):3682-92.
3. Griffith DC, et al. Antimicrob Agents Chemother. 2016 Sep 23;60(10):6326-32.

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