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Vaborbactam

CAS No. 1360457-46-0

Vaborbactam ( RPX-7009 )

Catalog No. M11479 CAS No. 1360457-46-0

A serine β-lactamase inhibitor that notably restores the activity of carbapenems against KPC-producing strains.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Vaborbactam
  • Note
    Research use only, not for human use.
  • Brief Description
    A serine β-lactamase inhibitor that notably restores the activity of carbapenems against KPC-producing strains.
  • Description
    A serine β-lactamase inhibitor that notably restores the activity of carbapenems against KPC-producing strains; restores meropenem activity for 72.7 to 98.1% of CPE isolates at ≤2 ug/ml; showes no antibacterial activity alone (MICs, >64 ug/ml).Bacterial Infection Approved
  • Synonyms
    RPX-7009
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    Infection
  • Indication
    Bacterial Infection

Chemical Information

  • CAS Number
    1360457-46-0
  • Formula Weight
    297.14
  • Molecular Formula
    C12H16BNO5S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    O=C(O)C[C@@H]1CC[C@H](NC(CC2=CC=CS2)=O)B(O)O1
  • Chemical Name
    1,2-Oxaborinane-6-acetic acid, 2-hydroxy-3-[[2-(2-thienyl)acetyl]amino]-, (3R,6S)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Castanheira M, et al. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5454-8.
2. Hecker SJ, et al. J Med Chem. 2015 May 14;58(9):3682-92.
3. Griffith DC, et al. Antimicrob Agents Chemother. 2016 Sep 23;60(10):6326-32.
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