Oxybenzone

Research use only, not for human use.

Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone.

Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays. (In Vitro):Oxybenzone (Benzophenone 3) (25 μM; 24 hours) decreases the relative RXRβ and RXRγ protein levels by 61 and 56%, respectively and increases the relative RXRα protein level by 49%.Oxybenzone (25-100 μM; 24 hours) induces an increase in caspase-3 levels in primary cultures of mouse neocortical cells at 7 DIV. Oxybenzone-induced apoptosis involves the activation of RXRα signaling and the impairment of RXRβ/RXRγ signaling. Oxybenzone (25 μM; 24 hours) inhibits global DNA methylation as well as reduced HDAC and HAT activities in mouse embryonic neuronal cells.

Oxybenzone (Benzophenone 3) (25 μM; 24 hours) decreases the relative RXRβ and RXRγ protein levels by 61 and 56%, respectively and increases the relative RXRα protein level by 49%.Oxybenzone (25-100 μM; 24 hours) induces an increase in caspase-3 levels in primary cultures of mouse neocortical cells at 7 DIV. Oxybenzone-induced apoptosis involves the activation of RXRα signaling and the impairment of RXRβ/RXRγ signaling. Oxybenzone (25 μM; 24 hours) inhibits global DNA methylation as well as reduced HDAC and HAT activities in mouse embryonic neuronal cells. Western Blot Analysis Cell Line:Mouse neocortical cells at 7 DIV Concentration:25 μM Incubation Time:24 hours Result:Exposure to Oxybenzone (25 μM) for 24 h decreased the relative RXRβ and RXRγ protein levels by 61 and 56%, respectively. Treatment with Oxybenzone (25 μM) increased the relative RXRα protein level by 49%.

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Oxybenzone, Benzophenone-3, 2-hydroxy-4-methoxybenzone, Eusolex-4360

Others

Other Targets

Others

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131-57-7

228.24

C14H12O3

>98% (HPLC)

Water: 69 mg/L .

O=C(C1=CC=C(OC)C=C1O)C2=CC=CC=C2

(2-hydroxy-4-methoxyphenyl)-phenylmethanone

(-20℃)

With Ice Pack

≥ 2 years