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Org-12962
CAS No. 132834-56-1
Org-12962 ( —— )
Catalog No. M26777 CAS No. 132834-56-1
Org-12962 is an effective and selective 5-HT2C receptor agonist pEC50: 7.01). Org-12962 shows antiaversive effects in a rat model of panic-like anxiety.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 37 | Get Quote |
|
| 10MG | 59 | Get Quote |
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| 25MG | 88 | Get Quote |
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| 50MG | 124 | Get Quote |
|
| 100MG | 177 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameOrg-12962
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NoteResearch use only, not for human use.
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Brief DescriptionOrg-12962 is an effective and selective 5-HT2C receptor agonist pEC50: 7.01). Org-12962 shows antiaversive effects in a rat model of panic-like anxiety.
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DescriptionOrg-12962 is an effective and selective 5-HT2C receptor agonist pEC50: 7.01). Org-12962 shows antiaversive effects in a rat model of panic-like anxiety. Org-12962 also shows high effacy for the 5-HT2A and 5-HT2B receptors (pEC50s: 6.38 and 6.28, respectively).(In Vivo):Org-12962 is dissolved or microsuspended in 0.3% v/v Tween 80 in physiological saline (NaCl 0.9%). Org-12962 (intraperitoneal injection; 0.3-3.2 mg/kg) obviously enhances the postinjection frequency thresholds for self-interruption (F3.71=11.40) .
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Synonyms——
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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RecptorHCV; Nucleoside Antimetabolite/Analog
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Research Area——
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Indication——
Chemical Information
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CAS Number132834-56-1
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Formula Weight265.7
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Molecular FormulaC10H11ClF3N3
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Purity>98% (HPLC)
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Solubility——
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SMILESFC(F)(F)c1ccc(nc1Cl)N1CCNCC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Steven S Carroll, et al. Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs. J Biol Chem. 2003 Apr 4;278(14):11979-84
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