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Olomoucine
CAS No. 101622-51-9
Olomoucine ( Olomoucine )
Catalog No. M10084 CAS No. 101622-51-9
A potent, ATP-competetive CDKs inhibitor with IC50 of 7, 7, 7, 3 uM for Cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, and Cdk/p35 kinase; also inhibits ERK1/MAP kinase (IC50=25 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 147 | Get Quote |
|
| 10MG | 237 | Get Quote |
|
| 25MG | 480 | Get Quote |
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| 50MG | 698 | Get Quote |
|
| 100MG | 972 | Get Quote |
|
| 500MG | 1953 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameOlomoucine
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, ATP-competetive CDKs inhibitor with IC50 of 7, 7, 7, 3 uM for Cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, and Cdk/p35 kinase; also inhibits ERK1/MAP kinase (IC50=25 uM).
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DescriptionA potent, ATP-competetive CDKs inhibitor with IC50 of 7, 7, 7, 3 uM for Cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, and Cdk/p35 kinase; also inhibits ERK1/MAP kinase (IC50=25 uM); inhibits the starfish oocyte G2/M transition in vivo.
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SynonymsOlomoucine
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PathwayAngiogenesis
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TargetCDK
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RecptorCDK
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Research Area——
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Indication——
Chemical Information
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CAS Number101622-51-9
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Formula Weight298.35
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Molecular FormulaC15H18N6O
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Purity>98% (HPLC)
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Solubility——
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SMILESCN1C=NC2=C(NCC3=CC=CC=C3)N=C(NCCO)N=C12
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Chemical Name2-(2-Hydroxyethylamino)-6- benzylamino-9-methylpurine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Vesely J, et al. Eur J Biochem. 1994 Sep 1;224(2):771-86.
2. Tsou YC, et al. Neurosci Lett. 2016 Aug 15;628:186-93.
3. Fei XF, et al. Brain Res. 2009 Apr 6;1264:85-97.
2. Tsou YC, et al. Neurosci Lett. 2016 Aug 15;628:186-93.
3. Fei XF, et al. Brain Res. 2009 Apr 6;1264:85-97.
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