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Olomoucine

CAS No. 101622-51-9

Olomoucine ( Olomoucine )

Catalog No. M10084 CAS No. 101622-51-9

A potent, ATP-competetive CDKs inhibitor with IC50 of 7, 7, 7, 3 uM for Cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, and Cdk/p35 kinase; also inhibits ERK1/MAP kinase (IC50=25 uM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 147 Get Quote
10MG 237 Get Quote
25MG 480 Get Quote
50MG 698 Get Quote
100MG 972 Get Quote
500MG 1953 Get Quote
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Biological Information

  • Product Name
    Olomoucine
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, ATP-competetive CDKs inhibitor with IC50 of 7, 7, 7, 3 uM for Cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, and Cdk/p35 kinase; also inhibits ERK1/MAP kinase (IC50=25 uM).
  • Description
    A potent, ATP-competetive CDKs inhibitor with IC50 of 7, 7, 7, 3 uM for Cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, and Cdk/p35 kinase; also inhibits ERK1/MAP kinase (IC50=25 uM); inhibits the starfish oocyte G2/M transition in vivo.
  • Synonyms
    Olomoucine
  • Pathway
    Angiogenesis
  • Target
    CDK
  • Recptor
    CDK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    101622-51-9
  • Formula Weight
    298.35
  • Molecular Formula
    C15H18N6O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CN1C=NC2=C(NCC3=CC=CC=C3)N=C(NCCO)N=C12
  • Chemical Name
    2-(2-Hydroxyethylamino)-6- benzylamino-9-methylpurine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Vesely J, et al. Eur J Biochem. 1994 Sep 1;224(2):771-86.
2. Tsou YC, et al. Neurosci Lett. 2016 Aug 15;628:186-93.
3. Fei XF, et al. Brain Res. 2009 Apr 6;1264:85-97.
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