Cart
sales@molnova.com
Olodaterol
CAS No. 868049-49-4
Olodaterol ( BI1744 CL )
Catalog No. M16305 CAS No. 868049-49-4
A potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2; shows >250 fold selectivity over hβ1; exerts a bronchodilatory efficacy over 24 h in dogs and guinea pigs in the absence of systemic pharmacodynamic effects.COPDPhase 3 Clinical
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 124 | In Stock |
|
| 5MG | 223 | In Stock |
|
| 10MG | 335 | In Stock |
|
| 25MG | 670 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameOlodaterol
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2; shows >250 fold selectivity over hβ1; exerts a bronchodilatory efficacy over 24 h in dogs and guinea pigs in the absence of systemic pharmacodynamic effects.COPDPhase 3 Clinical
-
DescriptionA potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2; shows >250 fold selectivity over hβ1; exerts a bronchodilatory efficacy over 24 h in dogs and guinea pigs in the absence of systemic pharmacodynamic effects.COPD Phase 3 Clinical
-
SynonymsBI1744 CL
-
PathwayAngiogenesis
-
TargetAdrenergic Receptor
-
Recptorβ2-adrenoceptor
-
Research AreaInflammation/Immunology
-
IndicationCOPD
Chemical Information
-
CAS Number868049-49-4
-
Formula Weight386.44
-
Molecular FormulaC21H26N2O5
-
Purity>98% (HPLC)
-
SolubilityH2O: 6.2 mg/mL
-
SMILESCC(C)(CC1=CC=C(C=C1)OC)NCC(C2=C3C(=CC(=C2)O)NC(=O)CO3)O
-
Chemical Name2H-1,4-Benzoxazin-3(4H)-one, 6-hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Bouyssou T, et al. Bioorg Med Chem Lett. 2010 Feb 15;20(4):1410-4.
2. Bouyssou T,J Pharmacol Exp Ther. 2010 Jul;334(1):53-62. et al.
3. Wex E, et al. Br J Pharmacol. 2015 Jul;172(14):3537-47.
2. Bouyssou T,J Pharmacol Exp Ther. 2010 Jul;334(1):53-62. et al.
3. Wex E, et al. Br J Pharmacol. 2015 Jul;172(14):3537-47.
molnova catalog
related products
-
Atenolol
A selective β1 receptor antagonist for treatment of hypertension.
-
3,4,5-Trimethoxyphen...
——
-
Bupranolol
Bupranolol is an antagonist of β2-adrenergic receptor,and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic.
