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Olodaterol
CAS No. 868049-49-4
Olodaterol ( BI1744 CL )
Catalog No. M16305 CAS No. 868049-49-4
A potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2; shows >250 fold selectivity over hβ1; exerts a bronchodilatory efficacy over 24 h in dogs and guinea pigs in the absence of systemic pharmacodynamic effects.COPDPhase 3 Clinical
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 124 | In Stock |
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| 5MG | 223 | In Stock |
|
| 10MG | 335 | In Stock |
|
| 25MG | 670 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameOlodaterol
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2; shows >250 fold selectivity over hβ1; exerts a bronchodilatory efficacy over 24 h in dogs and guinea pigs in the absence of systemic pharmacodynamic effects.COPDPhase 3 Clinical
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DescriptionA potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2; shows >250 fold selectivity over hβ1; exerts a bronchodilatory efficacy over 24 h in dogs and guinea pigs in the absence of systemic pharmacodynamic effects.COPD Phase 3 Clinical
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SynonymsBI1744 CL
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PathwayAngiogenesis
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TargetAdrenergic Receptor
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Recptorβ2-adrenoceptor
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Research AreaInflammation/Immunology
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IndicationCOPD
Chemical Information
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CAS Number868049-49-4
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Formula Weight386.44
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Molecular FormulaC21H26N2O5
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Purity>98% (HPLC)
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SolubilityH2O: 6.2 mg/mL
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SMILESCC(C)(CC1=CC=C(C=C1)OC)NCC(C2=C3C(=CC(=C2)O)NC(=O)CO3)O
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Chemical Name2H-1,4-Benzoxazin-3(4H)-one, 6-hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bouyssou T, et al. Bioorg Med Chem Lett. 2010 Feb 15;20(4):1410-4.
2. Bouyssou T,J Pharmacol Exp Ther. 2010 Jul;334(1):53-62. et al.
3. Wex E, et al. Br J Pharmacol. 2015 Jul;172(14):3537-47.
2. Bouyssou T,J Pharmacol Exp Ther. 2010 Jul;334(1):53-62. et al.
3. Wex E, et al. Br J Pharmacol. 2015 Jul;172(14):3537-47.
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