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Milveterol

CAS No. 652990-07-3

Milveterol ( GSK 159797 )

Catalog No. M15483 CAS No. 652990-07-3

Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Milveterol
  • Note
    Research use only, not for human use.
  • Brief Description
    Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays.
  • Description
    Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays, displays good β2/β1 selectivity (>300-fold); demonstrates high potency in vitro and long duration of action in a guinea pig model of bronchoprotection.Asthma Phase 2 Discontinued
  • Synonyms
    GSK 159797
  • Pathway
    Angiogenesis
  • Target
    Adrenergic Receptor
  • Recptor
    Adrenergic Receptor
  • Research Area
    Inflammation/Immunology
  • Indication
    Asthma

Chemical Information

  • CAS Number
    652990-07-3
  • Formula Weight
    435.52
  • Molecular Formula
    C25H29N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C1=CC=C(C=C1)C(CNC2=CC=C(C=C2)CCNCC(C3=CC(=C(C=C3)O)NC=O)O)O
  • Chemical Name
    N-(2-hydroxy-5-((R)-1-hydroxy-2-((4-(((R)-2-hydroxy-2-phenylethyl)amino)phenethyl)amino)ethyl)phenyl)formamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jacobsen JR, et al. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1213-8.
2. Fuso L, et al. Curr Med Chem. 2013;20(12):1477-95.
3. Jacobsen JR, et al. Bioorg Med Chem Lett. 2014 Jun 15;24(12):2625-30.
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